Amy Mansue, long honored as one of the top executives in the state, someone whose talent was recognized far beyond the health care sector, announced Tuesday that she will retire as the CEO of Inspira Health, effective Dec. 31.
Inspira President and COO Warren Moore will succeed her.
“Leading Inspira has been one of the great privileges of my career,” Mansue said. “I’m proud of what our team has accomplished and grateful for the trust of our communities.”
Mansue also expressed support for Moore.
“After working alongside Warren for many years, I know his ability to bring people together, navigate complex challenges and understand what our patients and neighbors count on us to deliver,” she said. “I have every confidence in his leadership of Inspira’s next chapter.”
During her tenure as CEO, Inspira said, Mansue expanded access to care and deepened Inspira’s investment in South Jersey. She championed a culture that puts patients and employees first and worked to emphasize workforce wellness so that those who care for others have the support they need.
Mansue has served as CEO of Inspira Health since August 2020, coming over from RWJBarnabas Health, where she was executive vice president and chief experience officer — roles she took after serving as president of the system’s Southern Region.
She also was one of three health care executives Gov. Phil Murphy picked in spring 2020 to oversee the state’s COVID-19 response. Each one ran a region, and Mansue had the Central Region.
Before that, Mansue was widely praised for the 13 years she spent as CEO of Children’s Specialized Hospital in Mountainside, the country’s largest inpatient pediatric rehabilitation hospital.
Her résumé runs through Trenton, too.
Mansue worked for Jim Florio as a health care policy staffer when he was in Congress and later in his policy office as governor. In 1993 she became a deputy commissioner in the state Department of Human Services, overseeing programs for children, people with developmental disabilities, mental health and Medicaid. She later served as deputy chief of staff to Gov. Jim McGreevey.
Her efforts in the business community were long admired, too.
In 2015, Mansue was named chair of the New Jersey Chamber of Commerce board, succeeding PSEG’s Ralph Izzo. She was only the second woman to hold the post and the first nonprofit executive to lead the board. In 2020, the State Chamber gave her its Thomas H. Kean Sr. Business Leadership Award.
She has also chaired the New Jersey Hospital Association.
State Chamber CEO Tom Bracken praised Mansue.
“Amy has been an extraordinary leader and tireless advocate for New Jersey’s business community for decades,” he said. “She served as chair of the New Jersey Chamber from 2015 to 2017 and has been actively involved in our organization for more than 20 years. Throughout her career, including her years in state government, she has been a trusted advocate and valuable resource on issues impacting businesses and New Jersey’s economy.
“Amy’s leadership, vision and dedication have made a lasting impact on New Jersey, particularly in the healthcare industry. Her retirement is a significant loss for our state’s business community.”
Moore will guide Inspira’s next phase of strategic development, the company said, by looking beyond traditional health care solutions to address the region’s most pressing needs. Drawing on his philosophy of collaboration over competition, he will pair Inspira’s clinical expertise with partners and local organizations.
His immediate priorities include opening the new tower at Inspira Medical Center Mullica Hill and optimizing the recently launched Epic, an electronic health record platform, to support care delivery. He will also carefully evaluate new technology that can give clinicians more time with patients.
Moore’s appointment follows his elevation to president in January 2026 and reflects his leadership across Inspira’s operations, quality, safety, growth and system integration since 2021. He brings more than 35 years of industry experience, according to Inspira.
Moore, who also served as CEO of Children’s Specialized Hospital, has worked with Mansue for more than two decades.
“The needs of South Jersey will always shape every decision we make at Inspira,” said Moore. “Our commitment is to ensure people can receive the services they need, close to home, and to earn their trust every day. I’m grateful to Amy for her leadership and partnership, and I’m looking forward to advancing Inspira’s mission and strengthening our impact across the communities we serve.”
Moore’s vision as CEO centers on further strengthening Inspira as one connected system where clinical excellence, employee safety and experience and community trust advance together. His approach will remain grounded in Inspira’s mission, with priorities guided by the needs of South Jersey.
Dawn Flitcraft, chair of the Inspira Health Network Board of Trustees, praised Mansue’s tenure and backed Moore’s elevation.
“The board’s responsibility is to prepare Inspira for what our communities need next,” she said. “Warren understands the challenges ahead and has proven his ability to unite teams around a shared vision and drive meaningful results. Building on the strong foundation Amy created, he is the right leader to guide Inspira through the rapidly evolving health care landscape while positioning the organization for continued success.”
